The present paper reports an optimized procedure for the efficient and fast HPLC separation of the enantiomeric pair of verapamil hydrochloride using an AGP chiral stationary phase. The influence of pH, flow-rate, temperature and concentration of organic modifier was investigated.
Separation of chiral compounds with alpha-acid glycoprotein as selector / Gamberini, Gianfranco; Ferioli, Valeria; Rustichelli, Cecilia; Vezzalini, Francesca. - STAMPA. - 1:(1990), pp. 139-139. (Intervento presentato al convegno Congresso Interdivisionale della SCI - CISCI 90 tenutosi a San Benedetto del Tronto nel 30 settembre - 5 ottobre 1990).
Separation of chiral compounds with alpha-acid glycoprotein as selector
GAMBERINI, Gianfranco;FERIOLI, Valeria;RUSTICHELLI, Cecilia;VEZZALINI, Francesca
1990
Abstract
The present paper reports an optimized procedure for the efficient and fast HPLC separation of the enantiomeric pair of verapamil hydrochloride using an AGP chiral stationary phase. The influence of pH, flow-rate, temperature and concentration of organic modifier was investigated.
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