Quercetin has been shown in animal and human skin to inhibit, in vitro an in vivo, the adverse effects caused by the sun UV rays. However, the skin protective activity of quercetin is hampered by its inefficient percutaneous penetration. Object of this study was the comparative evaluation of emulsions containing penetration enhancer or lipid noanoparticles on the skin penetration of the flavonoid.The study indicated that the nanoparticles achieved a targeting effect, favouring the localisation of the flavonoid in the superficial skin layers.
Influence of penetration enhancers and lipid nanoparticles on in vivo human skin penetration of quercetin / S., Scalia; Leo, Eliana Grazia; Iannuccelli, Valentina. - STAMPA. - ND:(2012), pp. 146-146. (Intervento presentato al convegno XXII Simposio ADRITELF - Firenze 2012 tenutosi a Firenze - Italia nel 13-16 settembre 2012).
Influence of penetration enhancers and lipid nanoparticles on in vivo human skin penetration of quercetin
LEO, Eliana Grazia;IANNUCCELLI, Valentina
2012
Abstract
Quercetin has been shown in animal and human skin to inhibit, in vitro an in vivo, the adverse effects caused by the sun UV rays. However, the skin protective activity of quercetin is hampered by its inefficient percutaneous penetration. Object of this study was the comparative evaluation of emulsions containing penetration enhancer or lipid noanoparticles on the skin penetration of the flavonoid.The study indicated that the nanoparticles achieved a targeting effect, favouring the localisation of the flavonoid in the superficial skin layers.
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