The aim of this work was the production of alginate/polymyxin B microparticles by spray-drying and cross-linking through Calcium ions and chitosan. Drug/polymer interaction, preparation parameters and microbiological drug activity in the microsystem were evalueted.
Microparticulate carrier for peroral administration of polymyxin B / Coppi, G., Iannuccelli, V., Bernabei, M.T.. - STAMPA. - ND:(2002), pp. 1347-1347. (4th World Meeting on Pharmaceutica, Biopharmaceutics, Pharmaceutical Technology Firenze - Italia 8-11- aprile 2002).
Microparticulate carrier for peroral administration of polymyxin B
COPPI, Gilberto;IANNUCCELLI, Valentina;BERNABEI, Maria Teresa
2002
Abstract
The aim of this work was the production of alginate/polymyxin B microparticles by spray-drying and cross-linking through Calcium ions and chitosan. Drug/polymer interaction, preparation parameters and microbiological drug activity in the microsystem were evalueted.
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