In order to evaluate the role of some preparative variables (viscosity grade and concentration of the polymer) on the release of soluble drugs, spherical matrices (beads) loaded with ambroxol hydrochloride were prepared by crosslinking with Al3+ sodium carboxymethylcellulose having different nominal viscosity grade in differently concentrated solutions.
Beads of cross-linked carboxymethylcellulose: effect of the viscosity grade and concentration of the polymer / Iannuccelli, Valentina; Coppi, Gilberto; Cameroni, Riccardo. - STAMPA. - ND:(1995), pp. 379-380. (Intervento presentato al convegno 1st World Meeting on Pharmaceutics, Biopharmaceutics, Pharmaceutical Technology tenutosi a Budapest - Ungheria nel 9-11 maggio 1995).