OOsteopenia and Osteoporosis are frequent complications of HIV infection and may be related with low trauma fractures. Gender differences, with an increased prevalence of osteoporosis in male patients, have been observed. We conducted a 104-week prospective, randomized, open-label study to evaluate the effects of alendronate, vitamin D, and calcium supplementation on bone metabolism and bone mineral density in patients with HIV infection. Interim analysis at 52 weeks is presented.
Alendronate reduces bone turnover in HIV-associated Osteopenia and Osteoporosis / Guaraldi, Giovanni; Orlando, G.; Maddeddu, G.; Vescini, F.; Ventura, Paolo; Campostrini, S.; Corradini, E.; Parise, N.; Solinas, P.; Calia, G. M.; Mura, M. S.; Nardini, Giulia; Beghetto, Barbara; Caudarella, R.; Esposito, Roberto. - STAMPA. - not applicable:(2004), pp. 103 (n 742)-103. (Intervento presentato al convegno 11th Conference on Retroviruses and Opportunistic Infections tenutosi a Moscon West san Francisco, CA, USA nel Febbraio 8-11, 2004).