The present invention relates to a technique for flow crystallization. The system comprises a container having a bottom surface defining a first plane, the container including at least two planar magnetic surfaces being arranged in a spaced-apart manner along a first plane and being substantially parallel to a second plane; a magnetization vector of each of the magnetic surfaces being perpendicularly to the surface, wherein the container is configured such that the first plane is substantially perpendicularly to the second plane; wherein a cavity formed in between the planar magnetic surfaces is configured to accommodate a racemic mixture including different enantiomers such that each magnetic surface interacts differently with each of the different enantiomers to thereby enable enantio-selective crystallization. Therefore, the system of the present invention is based on enantio-separation of the crystals using magnetic surfaces.

ENANTIO-SPECIFIC CRYSTALLIZATION SYSTEM AND METHOD THEREOF / Naaman, Ron; Tassinari, Francesco; Sang, Yutao; Santra, Kakali; Bhowmick, Debkumar. - (2021 Mar 11).

ENANTIO-SPECIFIC CRYSTALLIZATION SYSTEM AND METHOD THEREOF

Ron NAAMAN;Francesco TASSINARI;
2021

Abstract

The present invention relates to a technique for flow crystallization. The system comprises a container having a bottom surface defining a first plane, the container including at least two planar magnetic surfaces being arranged in a spaced-apart manner along a first plane and being substantially parallel to a second plane; a magnetization vector of each of the magnetic surfaces being perpendicularly to the surface, wherein the container is configured such that the first plane is substantially perpendicularly to the second plane; wherein a cavity formed in between the planar magnetic surfaces is configured to accommodate a racemic mixture including different enantiomers such that each magnetic surface interacts differently with each of the different enantiomers to thereby enable enantio-selective crystallization. Therefore, the system of the present invention is based on enantio-separation of the crystals using magnetic surfaces.
11-mar-2021
YEDA RESEARCH AND DEVELOPMENT CO. LTD
WO/2021/181393
Internazionale
Naaman, Ron; Tassinari, Francesco; Sang, Yutao; Santra, Kakali; Bhowmick, Debkumar
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1262063
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