Cradle to the grave Life Cycle Assessment of microwave assisted vs. conventional extraction for the obtainment of highly pure curcumin

Microwave assisted extraction of natural compounds is widely recognized as one of the most promising green extraction techniques, even if comprehensive comparisons with more conventional procedures are surprisingly scarce, being on the other hand limited to mere considerations concerning extraction time and yield. In this work, “cradle to the grave” environmental assessments of microwave assisted compared to conventional Soxhlet-based extraction procedures will be presented, for the particular case of curcumin molecule, extracted from Curcuma longa L., in view of its important antioxidant, anti-inflammatory and anticancer properties. The Life Cycle Assessment (LCA) methodology was applied, since it allows evaluating the environmental consequences associated with all the stages of the extraction process, thus including the crop production of the Indian plant, the subsequent production of the dried rhizomes, their commercialization, their transport, all the energy consumptions needed, the necessary laboratory facilities and their maintenance, together with the chemicals needed and their disposal treatments. The study was then completed by also comparing the obtained results with those of a particular synthetic strategy of curcumin, in order to establish the most environmentally friendly production procedure of this fundamental phytochemical.