Many epidemiological exposure variables have right-skewed distributions with sparse data at high exposure levels. Visualizing and estimating exposure-response relationships is further challenging for case-control studies, as the dependent variable is binary. We present improved approaches for estimating the exposure-response relation in such settings. Data from case-control studies of childhood cancer are used to illustrate the methods.
Estimating Exposure-Response Relationships in Case-Control Studies / Mary, Crespi Catherine; Leeka, Kheifets; Vinceti, Marco. - ELETTRONICO. - (2012). (Intervento presentato al convegno Joint Statistical Meetings 2012 tenutosi a San Diego USA nel July 28- August 2, 2012).
Estimating Exposure-Response Relationships in Case-Control Studies
VINCETI, Marco
2012
Abstract
Many epidemiological exposure variables have right-skewed distributions with sparse data at high exposure levels. Visualizing and estimating exposure-response relationships is further challenging for case-control studies, as the dependent variable is binary. We present improved approaches for estimating the exposure-response relation in such settings. Data from case-control studies of childhood cancer are used to illustrate the methods.
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