In order to assess the frequency of clinically relevant linezolid-resistant staphylococcal isolates, and the role of linezolid in maintaining and coselecting multiple resistance mechanisms (cfr, 23S rRNA, L3/L4 mutations), a prospective Italian study was performed from 2010 to 2011 to confirm the diffusion of three major multidrug-resistant clones (ST2, ST5, ST23).
Worrisome Trend of New Multiple Mechanisms of Linezolid Resistance in Staphylococcal Clones Diffused in Italy / F., Campanile; G., Mongelli; D., Bongiorno; C., Adembri; M., Ballardini; M., Falcone; F., Menichetti; A., Repetto; Sabia, Carla; A., Sartor; C., Scarparo; C., Tascini; M., Venditti; F., Zoppi; S., Stefani. - In: JOURNAL OF CLINICAL MICROBIOLOGY. - ISSN 0095-1137. - ELETTRONICO. - 51:(2013), pp. 1256-1259. [10.1128/JCM.00098-13]
Worrisome Trend of New Multiple Mechanisms of Linezolid Resistance in Staphylococcal Clones Diffused in Italy
SABIA, Carla;
2013
Abstract
In order to assess the frequency of clinically relevant linezolid-resistant staphylococcal isolates, and the role of linezolid in maintaining and coselecting multiple resistance mechanisms (cfr, 23S rRNA, L3/L4 mutations), a prospective Italian study was performed from 2010 to 2011 to confirm the diffusion of three major multidrug-resistant clones (ST2, ST5, ST23).
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