Multicentric renal angiomyolipoma is a rare form of benign tumor. However, its effective incidence as evaluated in autopsy studies may be as high as 8%. There are 2 main types of renal angiomyolipoma, that is isolated forms and those associated with other diseases, such as phakomatosis, polycystic kidneys and fibromuscular dysplasia. The tumor may also display malignant behavior with local invasiveness and regional lymph node involvement. However, the clinical course is benign and multicentricity is important for prognosis. Histopathological diagnosis often is difficult. Immunohistochemical analysis of surgical specimens using a panel of monoclonal antibodies, including HMB-45 and actin, enabled us to make a definitive diagnosis in 3 cases of multicentric renal angiomyolipoma.
Diagnostic ant therapeutic problems in multicentric renal angiomyolipoma / C., Tallarigo; R., Baldassarre; Bianchi, Giampaolo; L., Comunale; G., Olivo; M., Pea; F., Bonetti; G., Martignoni; G., Zamboni; G., Mobilio. - In: THE JOURNAL OF UROLOGY. - ISSN 0022-5347. - ELETTRONICO. - 148(6):(1992), pp. 1880-1884.
Diagnostic ant therapeutic problems in multicentric renal angiomyolipoma
BIANCHI, Giampaolo;
1992
Abstract
Multicentric renal angiomyolipoma is a rare form of benign tumor. However, its effective incidence as evaluated in autopsy studies may be as high as 8%. There are 2 main types of renal angiomyolipoma, that is isolated forms and those associated with other diseases, such as phakomatosis, polycystic kidneys and fibromuscular dysplasia. The tumor may also display malignant behavior with local invasiveness and regional lymph node involvement. However, the clinical course is benign and multicentricity is important for prognosis. Histopathological diagnosis often is difficult. Immunohistochemical analysis of surgical specimens using a panel of monoclonal antibodies, including HMB-45 and actin, enabled us to make a definitive diagnosis in 3 cases of multicentric renal angiomyolipoma.Pubblicazioni consigliate
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