17th EPA Congress

Aims: To evaluate the clinical and functional effects of cannabis abuse in patients at First Episode Psychosis (FEP) referring to Community Mental Health Centre (CMHC) “Bologna Ovest” and in patients admitted with a diagnosis of psychosis at the Modena Emergency Psychiatry Ward (EPW). Method: All FEP patients, aged 18-35, referring to CMCH “Bologna Ovest” in a 6-years period were evaluated and followed-up at 3 and 12 months. Of the 1559 psychiatric admissions at the Modena EPW in a 3-year period, those with a positive history for substance abuse were selected. Results: Among the 88 Bologna Ovest FEPs, 32% were cannabis abusers (FEP-c). In Bologna, FEP-c were more frequently natives (23.39% vs 31.13%; c sq=5.1; p=0.02) single (26.38% vs 0,0% c sq=7.3, p=0.007) and unemployed (13.50% vs 18.32%, c sq=2.4, p=0.1). Non FEP-c did not use any other drug (0.0% vs 26.1%, c sq=77.5; p< 0.001). A trend towards higher prevalence of hospital admission at follow-up was found for FEP-c (4.20% vs 2.4%, c sq=3.8, p=0.07). 22.0% of patients admitted at the Modena EPW had a positive history for substance abuse: of these, 7% were diagnosed with paranoid schizophrenia, which significantly correlated with the use of cannabinoids (alone or in association). Discussion: Our results enlighten that cannabis use is frequent among psychotic patients admitted to hospital and worsens clinical course of FEP patients, consistently with previous evidence (Hambrecht & Hafner, 1996; Hafner et al., 2004).

Cannabis abuse at first episode psychosis (FEP): Data from mental health centres in modena and Bologna, Italy / I., Tarricone; E., Rossi; D., Pecile; A., Castellani; A., Paparelli; V., Bandieri; Ferrari, Silvia; L., Pingani; R., Di Lorenzo; Rigatelli, Marco; D., Berardi. - In: EUROPEAN PSYCHIATRY. - ISSN 0924-9338. - ELETTRONICO. - 24, supp. 1:(2009), pp. S145-S145. (Intervento presentato al convegno 17th Congress of the European Psychiatric Association tenutosi a Lisbon nel January 2009).

Cannabis abuse at first episode psychosis (FEP): Data from mental health centres in modena and Bologna, Italy

FERRARI, Silvia;RIGATELLI, Marco;
2009

Abstract

Aims: To evaluate the clinical and functional effects of cannabis abuse in patients at First Episode Psychosis (FEP) referring to Community Mental Health Centre (CMHC) “Bologna Ovest” and in patients admitted with a diagnosis of psychosis at the Modena Emergency Psychiatry Ward (EPW). Method: All FEP patients, aged 18-35, referring to CMCH “Bologna Ovest” in a 6-years period were evaluated and followed-up at 3 and 12 months. Of the 1559 psychiatric admissions at the Modena EPW in a 3-year period, those with a positive history for substance abuse were selected. Results: Among the 88 Bologna Ovest FEPs, 32% were cannabis abusers (FEP-c). In Bologna, FEP-c were more frequently natives (23.39% vs 31.13%; c sq=5.1; p=0.02) single (26.38% vs 0,0% c sq=7.3, p=0.007) and unemployed (13.50% vs 18.32%, c sq=2.4, p=0.1). Non FEP-c did not use any other drug (0.0% vs 26.1%, c sq=77.5; p< 0.001). A trend towards higher prevalence of hospital admission at follow-up was found for FEP-c (4.20% vs 2.4%, c sq=3.8, p=0.07). 22.0% of patients admitted at the Modena EPW had a positive history for substance abuse: of these, 7% were diagnosed with paranoid schizophrenia, which significantly correlated with the use of cannabinoids (alone or in association). Discussion: Our results enlighten that cannabis use is frequent among psychotic patients admitted to hospital and worsens clinical course of FEP patients, consistently with previous evidence (Hambrecht & Hafner, 1996; Hafner et al., 2004).
2009
24, supp. 1
S145
S145
I., Tarricone; E., Rossi; D., Pecile; A., Castellani; A., Paparelli; V., Bandieri; Ferrari, Silvia; L., Pingani; R., Di Lorenzo; Rigatelli, Marco; D., Berardi
Cannabis abuse at first episode psychosis (FEP): Data from mental health centres in modena and Bologna, Italy / I., Tarricone; E., Rossi; D., Pecile; A., Castellani; A., Paparelli; V., Bandieri; Ferrari, Silvia; L., Pingani; R., Di Lorenzo; Rigatelli, Marco; D., Berardi. - In: EUROPEAN PSYCHIATRY. - ISSN 0924-9338. - ELETTRONICO. - 24, supp. 1:(2009), pp. S145-S145. (Intervento presentato al convegno 17th Congress of the European Psychiatric Association tenutosi a Lisbon nel January 2009).
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