Biliary tract complications after liver transplantation represent a source of morbidity and mortality. Performing an analysis to evaluate whether HIV infection and its related comorbidities, such as HIV-related cholangiopathy, could be an unknown risk factor for biliary stricture, we found that HIV-positivity could lead to greater susceptibility to biliary damage. The pathogenesis of the damage seems to involve the pretransplant immunological status and the number and type of posttransplant infections, although further studies are needed.
Does HIV-related cholangiopathy exist in the setting of liver transplantation? / Spaggiari, Mario; Ballarin, Roberto; DI BENEDETTO, Fabrizio; R., Montalti; N. d., Ruvo; Cautero, Nicola; G., Guerrini; Gerunda, Giorgio Enrico. - In: AIDS. - ISSN 1473-5571. - STAMPA. - 24:(2010), pp. 1072-1075. [10.1097/QAD.0b013e3283382f4b]
Does HIV-related cholangiopathy exist in the setting of liver transplantation?
SPAGGIARI, Mario;BALLARIN, Roberto;DI BENEDETTO, Fabrizio;CAUTERO, Nicola;GERUNDA, Giorgio Enrico
2010
Abstract
Biliary tract complications after liver transplantation represent a source of morbidity and mortality. Performing an analysis to evaluate whether HIV infection and its related comorbidities, such as HIV-related cholangiopathy, could be an unknown risk factor for biliary stricture, we found that HIV-positivity could lead to greater susceptibility to biliary damage. The pathogenesis of the damage seems to involve the pretransplant immunological status and the number and type of posttransplant infections, although further studies are needed.
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