Chondroitin sulfate is a biomolecule which has increasingly focused the interest of many research groups due to its possible anti-inflammatory activity. This communication briefly summarises the chondroitin sulfate anti-inflammatory activity and its capacity to affect cartilage metabolism in in vitro studies and in animals and humans models. In particular, the effect of chondroitin sulfate and derivatives on elastase activity in vitro will be presented and the capacity of this natural polymer to inhibit the IgE-mediated response and edema, synovitis and destruction of the articular cartilage in mice, and to inhibit proteolytic and degradative activities in men will be discussed.
Anti-inflammatory activity of chondroitin sulfate / Volpi, Nicola. - STAMPA. - (2007), pp. N/A-N/A. (Intervento presentato al convegno Workshop di microscopia elettronica a scansione ambientale e microscopia confocale tenutosi a Barcellona, Spagna nel 13-16 giugno).
Anti-inflammatory activity of chondroitin sulfate
VOLPI, Nicola
2007
Abstract
Chondroitin sulfate is a biomolecule which has increasingly focused the interest of many research groups due to its possible anti-inflammatory activity. This communication briefly summarises the chondroitin sulfate anti-inflammatory activity and its capacity to affect cartilage metabolism in in vitro studies and in animals and humans models. In particular, the effect of chondroitin sulfate and derivatives on elastase activity in vitro will be presented and the capacity of this natural polymer to inhibit the IgE-mediated response and edema, synovitis and destruction of the articular cartilage in mice, and to inhibit proteolytic and degradative activities in men will be discussed.Pubblicazioni consigliate
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