Little is known about the effects of the menstrual cycle on brain activity in primates. Here, we use 18F-fluorodeoxyglucose positron emission tomography to monitor changes in resting brain glucose metabolism across the menstrual cycle in female rhesus monkeys. Results showed greater activity in right lateral orbitofrontal cortex, a region involved in processing negatively valenced emotional stimuli, in the follicular compared with luteal phase. Estradiol levels were negatively correlated with activity in cortical and brainstem regions involved in emotional processing, and positively correlated with activity in areas involved in cognitive control and emotion regulation. In summary, the data suggest that in primates, fluctuations of ovarian hormones across the menstrual cycle influence activity in brain areas involved in emotion and its regulation.

Effect of the menstrual cycle on resting brain glucose metabolism in female rhesus monkeys / Rilling, Jk; Lacreus, A; Barks, Sk; Elfenbein, Ha; Pagnoni, Giuseppe; Votaw, Jr; Herndon, Jg. - In: NEUROREPORT. - ISSN 0959-4965. - STAMPA. - 19:5(2008), pp. 537-541. [10.1097/WNR.0b013e3282f8b086]

Effect of the menstrual cycle on resting brain glucose metabolism in female rhesus monkeys

PAGNONI, Giuseppe;
2008

Abstract

Little is known about the effects of the menstrual cycle on brain activity in primates. Here, we use 18F-fluorodeoxyglucose positron emission tomography to monitor changes in resting brain glucose metabolism across the menstrual cycle in female rhesus monkeys. Results showed greater activity in right lateral orbitofrontal cortex, a region involved in processing negatively valenced emotional stimuli, in the follicular compared with luteal phase. Estradiol levels were negatively correlated with activity in cortical and brainstem regions involved in emotional processing, and positively correlated with activity in areas involved in cognitive control and emotion regulation. In summary, the data suggest that in primates, fluctuations of ovarian hormones across the menstrual cycle influence activity in brain areas involved in emotion and its regulation.
2008
19
5
537
541
Effect of the menstrual cycle on resting brain glucose metabolism in female rhesus monkeys / Rilling, Jk; Lacreus, A; Barks, Sk; Elfenbein, Ha; Pagnoni, Giuseppe; Votaw, Jr; Herndon, Jg. - In: NEUROREPORT. - ISSN 0959-4965. - STAMPA. - 19:5(2008), pp. 537-541. [10.1097/WNR.0b013e3282f8b086]
Rilling, Jk; Lacreus, A; Barks, Sk; Elfenbein, Ha; Pagnoni, Giuseppe; Votaw, Jr; Herndon, Jg
File in questo prodotto:
File Dimensione Formato  
Rilling2008a.pdf

Accesso riservato

Tipologia: Versione pubblicata dall'editore
Dimensione 160.37 kB
Formato Adobe PDF
160.37 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/609144
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 6
social impact