A better understanding of the origin and evolution of nevi may help elucidate the pathways involved in melanoma-genesis. Herein we will present our theory of 2 distinct pathways to nevogenesis. We postulate, based on clinical observations and research data, that junctional nevi and superficial spreading melanomas arise from epidermal melanocytes, whereas dermal nevi and nodular melanomas originate in the dermis.
The epidermal and dermal origin of melanocytic tumors: Theoretical considerations based on epidemiologic, clinical, and histopathologic findings / I., Zalaudek; B., Leinweber; R., Hofmann Wellenhof; A., Scope; A. A., Marghoob; G., Ferrara; Pellacani, Giovanni; G., Argenziano; H. P., Soyer. - In: AMERICAN JOURNAL OF DERMATOPATHOLOGY. - ISSN 0193-1091. - STAMPA. - 30:4(2008), pp. 403-406. [10.1097/DAD.0b013e3181734e9a]
The epidermal and dermal origin of melanocytic tumors: Theoretical considerations based on epidemiologic, clinical, and histopathologic findings
PELLACANI, Giovanni;
2008
Abstract
A better understanding of the origin and evolution of nevi may help elucidate the pathways involved in melanoma-genesis. Herein we will present our theory of 2 distinct pathways to nevogenesis. We postulate, based on clinical observations and research data, that junctional nevi and superficial spreading melanomas arise from epidermal melanocytes, whereas dermal nevi and nodular melanomas originate in the dermis.Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris