A better understanding of the origin and evolution of nevi may help elucidate the pathways involved in melanoma-genesis. Herein we will present our theory of 2 distinct pathways to nevogenesis. We postulate, based on clinical observations and research data, that junctional nevi and superficial spreading melanomas arise from epidermal melanocytes, whereas dermal nevi and nodular melanomas originate in the dermis.

The epidermal and dermal origin of melanocytic tumors: Theoretical considerations based on epidemiologic, clinical, and histopathologic findings / I., Zalaudek; B., Leinweber; R., Hofmann Wellenhof; A., Scope; A. A., Marghoob; G., Ferrara; Pellacani, Giovanni; G., Argenziano; H. P., Soyer. - In: AMERICAN JOURNAL OF DERMATOPATHOLOGY. - ISSN 0193-1091. - STAMPA. - 30:4(2008), pp. 403-406. [10.1097/DAD.0b013e3181734e9a]

The epidermal and dermal origin of melanocytic tumors: Theoretical considerations based on epidemiologic, clinical, and histopathologic findings

PELLACANI, Giovanni;
2008

Abstract

A better understanding of the origin and evolution of nevi may help elucidate the pathways involved in melanoma-genesis. Herein we will present our theory of 2 distinct pathways to nevogenesis. We postulate, based on clinical observations and research data, that junctional nevi and superficial spreading melanomas arise from epidermal melanocytes, whereas dermal nevi and nodular melanomas originate in the dermis.
2008
30
4
403
406
The epidermal and dermal origin of melanocytic tumors: Theoretical considerations based on epidemiologic, clinical, and histopathologic findings / I., Zalaudek; B., Leinweber; R., Hofmann Wellenhof; A., Scope; A. A., Marghoob; G., Ferrara; Pellacani, Giovanni; G., Argenziano; H. P., Soyer. - In: AMERICAN JOURNAL OF DERMATOPATHOLOGY. - ISSN 0193-1091. - STAMPA. - 30:4(2008), pp. 403-406. [10.1097/DAD.0b013e3181734e9a]
I., Zalaudek; B., Leinweber; R., Hofmann Wellenhof; A., Scope; A. A., Marghoob; G., Ferrara; Pellacani, Giovanni; G., Argenziano; H. P., Soyer
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/590611
Citazioni
  • ???jsp.display-item.citation.pmc??? 8
  • Scopus 28
  • ???jsp.display-item.citation.isi??? 20
social impact