In order to compare the effects on gallstone dissolution of three different doses of UDCA (4, 8 and 12 mg/kg/day), a controlled trial was carried out with seventy-one patients. The dissolution rate was higher in the group treated with the highest dose. Stone size was the major factor affecting the outcome of treatment, with a significantly higher success rate in patients with gallstones less than 10 mm than with stones greater than 10 mm.
Gallstone dissolution after 6 months of UDCA / M., Podda; M., Zuin; N., Carulli; PONZ DE LEON, Maurizio; M. L., Dioguardi. - In: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH. - ISSN 0300-0605. - STAMPA. - 10:(1982), pp. 59-63. [10.1177/030006058201000112]
Gallstone dissolution after 6 months of UDCA
PONZ DE LEON, Maurizio;
1982
Abstract
In order to compare the effects on gallstone dissolution of three different doses of UDCA (4, 8 and 12 mg/kg/day), a controlled trial was carried out with seventy-one patients. The dissolution rate was higher in the group treated with the highest dose. Stone size was the major factor affecting the outcome of treatment, with a significantly higher success rate in patients with gallstones less than 10 mm than with stones greater than 10 mm.
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