The present study reports a comparative analysis of the behavioural effects induced in rats by three structurally similar compounds. One of them is the D2 dopamine agonist RU 24213, the others are newly-synthesized drugs whose selective affinity for D2 receptors has been established in priliminary binding studies. Discussion centers on the possible relationship between their chemical structure and behavioural activity.
A COMPARATIVE BEHAVIOURAL ANALYSIS IN RATS OF THE D2 AGONIST RU 24213 AND TWO NEW STRUCTURALLY SIMILAR COMPOUNDS / Ferrari, Francesca; F., Claudi; G., Giorgioni; Giuliani, Daniela. - In: PHARMACEUTICAL AND PHARMACOLOGICAL LETTERS. - ISSN 0939-9488. - STAMPA. - 3:(1993), pp. 59-62.
A COMPARATIVE BEHAVIOURAL ANALYSIS IN RATS OF THE D2 AGONIST RU 24213 AND TWO NEW STRUCTURALLY SIMILAR COMPOUNDS
FERRARI, Francesca;GIULIANI, Daniela
1993
Abstract
The present study reports a comparative analysis of the behavioural effects induced in rats by three structurally similar compounds. One of them is the D2 dopamine agonist RU 24213, the others are newly-synthesized drugs whose selective affinity for D2 receptors has been established in priliminary binding studies. Discussion centers on the possible relationship between their chemical structure and behavioural activity.
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