The present study was aimed at identifying themolecular profile characteristic of the healthy humangastric mucosa.Ex vivo HR-MAS magnetic resonance spectroscopy performed at 9.4 Tesla (400.13 MHz for 1H) on gastric specimens collected during endoscopy, permits the identification of more than forty species giving a detailed picture of the biochemical pattern of the gastric tissues. These preliminary data will be used for a comparison with gastric preneoplastic and neoplastic situations. Moreover, the full knowledge of the biochemical pattern of the healthy gastrictissues is the necessary presupposition for the application of magnetic resonance spectroscopy directly in vivo.
Molecular characterization of human gastric mucosa by HR-MAS Magnetic Resonance Spectroscopy / V., Tugnoli; Mucci, Adele; Schenetti, Luisa; C., Calabrese; G., Di Febo; Rossi, Maria Cecilia; R., Tosi. - In: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. - ISSN 1107-3756. - STAMPA. - 14:6(2004), pp. 1065-1071. [10.3892/ijmm.14.6.1065]
Molecular characterization of human gastric mucosa by HR-MAS Magnetic Resonance Spectroscopy
MUCCI, Adele;SCHENETTI, Luisa;ROSSI, Maria Cecilia;
2004
Abstract
The present study was aimed at identifying themolecular profile characteristic of the healthy humangastric mucosa.Ex vivo HR-MAS magnetic resonance spectroscopy performed at 9.4 Tesla (400.13 MHz for 1H) on gastric specimens collected during endoscopy, permits the identification of more than forty species giving a detailed picture of the biochemical pattern of the gastric tissues. These preliminary data will be used for a comparison with gastric preneoplastic and neoplastic situations. Moreover, the full knowledge of the biochemical pattern of the healthy gastrictissues is the necessary presupposition for the application of magnetic resonance spectroscopy directly in vivo.
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