Stupor is a diagnostic challenge at emergency department. Differential diagnosis includes idiopathic recurrent stupor, formerly attributed to "endozepine-4" accumulation. This condition has been recently questioned because many suspected cases resulted in exogenous benzodiazepine intake that eludes the conventional toxicological assay. In case of unexplained recurrent stupor, to extend the benzodiazepine search in nonconventional matrices can allow unmasking of hidden toxic behavior.
Segmental hair testing of triazolam to unmask a suspected case of idiopathic recurrent Stupor / Postiglione, Emanuela; Antelmi, Elena; Moresco, Monica; Pichini, Simona; Pizza, Fabio; Plazzi, Giuseppe; Busardò, Francesco Paolo. - In: JOURNAL OF CLINICAL SLEEP MEDICINE. - ISSN 1550-9389. - 14:4(2018), pp. 697-699. [10.5664/jcsm.7078]
Segmental hair testing of triazolam to unmask a suspected case of idiopathic recurrent Stupor
Moresco, Monica;Plazzi, Giuseppe;
2018
Abstract
Stupor is a diagnostic challenge at emergency department. Differential diagnosis includes idiopathic recurrent stupor, formerly attributed to "endozepine-4" accumulation. This condition has been recently questioned because many suspected cases resulted in exogenous benzodiazepine intake that eludes the conventional toxicological assay. In case of unexplained recurrent stupor, to extend the benzodiazepine search in nonconventional matrices can allow unmasking of hidden toxic behavior.
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