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Objective: To study the prevalence of congenital syphilis and its risk factors in Italy. Study design: Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. Results: Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100 000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Discussion: Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Conclusion: Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
Congenital syphilis in Italy: A multicentre study / Tridapalli, E.; Capretti, M. G.; Reggiani, M. L. B.; Stronati, M.; Faldella, G.; Auriti, C.; Balata, A.; Barera, G.; Bennato, E.; Berardi, A.; Bolognesi, S.; Bonomi, A.; Boulos, F.; Brambilla, C.; Branchi, M.; Cabiati, G.; Caddia, V.; Calzetti, G.; Campanile, A.; Cataldo, P.; Cavagna, R.; Chiarolini, A.; Ciccia, M.; Ciccotti, R.; Ciofalo, A.; Contiero, R.; Corona, G.; Corso, G.; Costa, L.; Coviello, C.; Cristofori, G.; Crivellaro, C.; Cucchi, G.; Danese, G.; Da Riol, R.; Decembrino, L.; Delogu, A.; Del Vecchio, A.; Da Riol, R.; De Sanctis, L.; Di Chiara, G.; Di Comite, A.; Di Grande, E. C.; D'Onofrio, A. M.; Faccia, P.; Ferrari, D.; Fortunati, P.; Gabriella, T. L.; Galimberti, D.; Garzia, P.; Giorgino, M.; Gragnani, S.; Gurrido, R.; Lacaita, G.; Leone, G.; Lipari, A.; Lorenzini, C.; Lo Sciotto, P.; Malagutti, L.; Maschio, F.; Matteucci, L.; Migliozzi, L.; Mileti, F.; Murgia, M. R.; Navone, M.; Nosari, N.; Notarmuzi, M. L.; Pagliani, L.; Paino, D.; Papa, I.; Papili, F.; Parisi, G.; Perocchi, F.; Perona, A.; Pirrami, R.; Pitassi, I.; Priore, ; Raponi, S.; Rizzo, V.; Robieux, I.; Rossi, A.; Ruffini, E.; Russo, R.; Salvi, G.; Serra, L.; Sferlazzo, S.; Solimano, T.; Spadaro, V.; Stramare, D.; Stroppiana, P.; Tarquini, E.; Taurino, L.; Tedoldi, S.; Tessariol, D.; Travaglio, M. D.; Vagnarelli, F.; Valente, A.; Valentini, P.; Volta, A.; Zaffaroni, M.. - In: ARCHIVES OF DISEASE IN CHILDHOOD. FETAL AND NEONATAL EDITION. - ISSN 1359-2998. - 97:3(2012), pp. F211-F213. [10.1136/adc.2010.183863]
Objective: To study the prevalence of congenital syphilis and its risk factors in Italy. Study design: Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. Results: Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100 000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Discussion: Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Conclusion: Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1204037
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