Sorafenib is associated with multiple adverse events (AEs), potentially causing its permanent interruption. The impact of the physicians experience on the management of these AEs and the relative implications on clinical outcomes are unknown. We verified if the AEs management changed over time and if these modifications impacted on treatment duration and overall survival (OS).
Management of adverse events with tailored sorafenib dosing prolongs survival of hepatocellular carcinoma patients / Tovoli, Francesco; Ielasi, Luca; Casadei Gardini, Andrea; Granito, Alessandro; Foschi, Francesco Giuseppe; Rovesti, Giulia; Negrini, Giulia; Orsi, Giulia; Renzulli, Matteo; Piscaglia, Fabio. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - 71:6(2019), pp. 1175-1183. [10.1016/j.jhep.2019.08.015]
Management of adverse events with tailored sorafenib dosing prolongs survival of hepatocellular carcinoma patients
CASADEI GARDINI, Andrea;ROVESTI, GIULIA;NEGRINI, GIULIA;ORSI, GIULIA;
2019
Abstract
Sorafenib is associated with multiple adverse events (AEs), potentially causing its permanent interruption. The impact of the physicians experience on the management of these AEs and the relative implications on clinical outcomes are unknown. We verified if the AEs management changed over time and if these modifications impacted on treatment duration and overall survival (OS).
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JHEPAT-D-19-00748_R1.pdf
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AAM - Versione dell'autore revisionata e accettata per la pubblicazione
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4.6 MB
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4.6 MB | Adobe PDF | Visualizza/Apri |
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VOR_Management of adverse events.pdf
Open access
Tipologia:
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768.55 kB
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Adobe PDF
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768.55 kB | Adobe PDF | Visualizza/Apri |
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