We present a retrospective monocentric analysis performed on 121 patients referred to Our Unit from 2000 to 2016 with evidence of cryoglobulinemia. According to Brouet classification type III was the most common cryoglobulinemia (48%), followed by type II (23%) and type I (6%); 10% were type II-III.. Based on clinical and laboratory data we confirm cryoglobulinemic syndrome with renal involvment as a prognostically unfavourable feature, with increased mortality and progression to end stage renal disease. Patients with mixed cryoglobulinemia had a similar outcome.
CRYOGLOBULIN MEDIATED KIDNEY DISEASE: HCV INFECTION, HISTOLOGICAL PATTERNS, ROLE OF RITUXIMAB. MONOCENTRIC REPORT / Cerami, Caterina; Scichilone, Laura Maria; Mascia, Maria Teresa; Daniele, Camppioli; Cappelli, Gianni. - In: NEPHROLOGY DIALYSIS TRANSPLANTATION. - ISSN 0931-0509. - 33:Suppl 1(2018), pp. 18-18. (Intervento presentato al convegno 55th ERA-EDTA CONGRESS tenutosi a Copenhagen Denmark nel May 24th - 27th 2018) [10.1093/ndt/gfy104.FP123].
CRYOGLOBULIN MEDIATED KIDNEY DISEASE: HCV INFECTION, HISTOLOGICAL PATTERNS, ROLE OF RITUXIMAB. MONOCENTRIC REPORT
Cerami, CaterinaInvestigation
;Scichilone, Laura MariaInvestigation
;Maria Teresa MasciaConceptualization
;Gianni CappelliSupervision
2018
Abstract
We present a retrospective monocentric analysis performed on 121 patients referred to Our Unit from 2000 to 2016 with evidence of cryoglobulinemia. According to Brouet classification type III was the most common cryoglobulinemia (48%), followed by type II (23%) and type I (6%); 10% were type II-III.. Based on clinical and laboratory data we confirm cryoglobulinemic syndrome with renal involvment as a prognostically unfavourable feature, with increased mortality and progression to end stage renal disease. Patients with mixed cryoglobulinemia had a similar outcome.
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