Similarly to other countries, T1D is the most frequent diagnosis in Italian diabetic patients !18 years, while a striking disparity, likely due to different lifestyle and genetic background, is observed between the rate of T2D of this study (1.1%, in keeping with European reports of 0.24–1.4%) and the SEARCH data from US (about 11%). At further variance with other Western countries (e.g. Norwegian registry, the DPV-Wiss study, the SEARCH study), the prevalence of MD in Italy is very high. This could depend on the fact that broader attention is devoted to MD in Italy than in the US, and also on the fact that genetic testing is easily accessible and free of charge. The close follow-up of patients with incidental hyperglycemia likely accounts for the very high rate of GCK/MODY2 mutations, the most frequent MODY type in Italy.

Aetiological Diagnosis of Diabetes in Italian Diabetic Children and Adolescents / Delvecchio, Maurizio; Salzano, Giuseppina; Mozzillo, Enza; Frontino, Giulio; Patera, Patrizia; Toni, Sonia; Rabbone, Ivana; Cherubini, Valentino; Tumini, Stefano; D’Annunzio, Giuseppe; Iughetti, Lorenzo; Maltoni, Giulio; Cauvin, Vittoria; Marigliano, Marco; Barbetti, Fabrizio. - In: HORMONE RESEARCH IN PAEDIATRICS. - ISSN 1663-2818. - STAMPA. - 84:S 1(2015), pp. 81-81. (Intervento presentato al convegno 54th Annual ESPE Meeting tenutosi a Barcelona).

Aetiological Diagnosis of Diabetes in Italian Diabetic Children and Adolescents

IUGHETTI, Lorenzo;
2015

Abstract

Similarly to other countries, T1D is the most frequent diagnosis in Italian diabetic patients !18 years, while a striking disparity, likely due to different lifestyle and genetic background, is observed between the rate of T2D of this study (1.1%, in keeping with European reports of 0.24–1.4%) and the SEARCH data from US (about 11%). At further variance with other Western countries (e.g. Norwegian registry, the DPV-Wiss study, the SEARCH study), the prevalence of MD in Italy is very high. This could depend on the fact that broader attention is devoted to MD in Italy than in the US, and also on the fact that genetic testing is easily accessible and free of charge. The close follow-up of patients with incidental hyperglycemia likely accounts for the very high rate of GCK/MODY2 mutations, the most frequent MODY type in Italy.
2015
84
81
81
Delvecchio, Maurizio; Salzano, Giuseppina; Mozzillo, Enza; Frontino, Giulio; Patera, Patrizia; Toni, Sonia; Rabbone, Ivana; Cherubini, Valentino; Tumini, Stefano; D’Annunzio, Giuseppe; Iughetti, Lorenzo; Maltoni, Giulio; Cauvin, Vittoria; Marigliano, Marco; Barbetti, Fabrizio
Aetiological Diagnosis of Diabetes in Italian Diabetic Children and Adolescents / Delvecchio, Maurizio; Salzano, Giuseppina; Mozzillo, Enza; Frontino, Giulio; Patera, Patrizia; Toni, Sonia; Rabbone, Ivana; Cherubini, Valentino; Tumini, Stefano; D’Annunzio, Giuseppe; Iughetti, Lorenzo; Maltoni, Giulio; Cauvin, Vittoria; Marigliano, Marco; Barbetti, Fabrizio. - In: HORMONE RESEARCH IN PAEDIATRICS. - ISSN 1663-2818. - STAMPA. - 84:S 1(2015), pp. 81-81. (Intervento presentato al convegno 54th Annual ESPE Meeting tenutosi a Barcelona).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1128140
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