The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent of life-threatening infections in immunocompromised subjects. A unique characteristic of Cryptococcus species is the presence of a polysaccharide capsule, which is essential for virulence and endows Cryptococcus with potent immunoregulatory properties. This review provides an overview of the immunological properties of the principal components of C. neoformans capsule.
Elucidating the immunological function of the Cryptococcus neoformans capsule / Anna, Vecchiarelli; Pericolini, Eva; Elena, Gabrielli; Samyr, Kenno; Stefano, Perito; Elio, Cenci; Claudia, Monari. - In: FUTURE MICROBIOLOGY. - ISSN 1746-0913. - 8:9(2013), pp. 1107-1116. [10.2217/fmb.13.84]
Elucidating the immunological function of the Cryptococcus neoformans capsule
PERICOLINI, Eva;Samyr Kenno;
2013
Abstract
The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent of life-threatening infections in immunocompromised subjects. A unique characteristic of Cryptococcus species is the presence of a polysaccharide capsule, which is essential for virulence and endows Cryptococcus with potent immunoregulatory properties. This review provides an overview of the immunological properties of the principal components of C. neoformans capsule.
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Descrizione: Vecchiarelli A. et al, Future Microbiology 2013
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