Estrogen and progesterone are the most important ovarian steroid hormones regulating female fertility. They have a profound effect on the central nervous system. Target functions of sex steroids in the brain are: pituitary and hypothalamic hormone release, thermoregulatory and cardiocirculatory activities and behavior and mood changes. Furthermore, several studies have shown a correlation between brain neurotransmitters, neuropeptides and sex steroid hormones: they influence synthesis and release of norepinephrine, dopamine, serotonin, gonadotropin releasing hormone, β-endorphin, corticotropin releasing factor and prolactin. Thus, oral hormone contraceptives inhibit the ovulatory process by blocking the activity of the hypothalamus-pituitary-gonadal axis. This inhibitory effect seems to be due to the action of both estrogens and progestins.

Effects of sex steroid hormones on the neuroendocrine system / Genazzani, A. R.; Lucchesi, A.; Stomati, M.; Catarsi, S.; Genazzani, Alessandro; Criscuolo, M.; Petraglia, F.. - In: THE EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. - ISSN 1362-5187. - STAMPA. - 2:(1997), pp. 63-69.

Effects of sex steroid hormones on the neuroendocrine system

GENAZZANI, Alessandro;
1997

Abstract

Estrogen and progesterone are the most important ovarian steroid hormones regulating female fertility. They have a profound effect on the central nervous system. Target functions of sex steroids in the brain are: pituitary and hypothalamic hormone release, thermoregulatory and cardiocirculatory activities and behavior and mood changes. Furthermore, several studies have shown a correlation between brain neurotransmitters, neuropeptides and sex steroid hormones: they influence synthesis and release of norepinephrine, dopamine, serotonin, gonadotropin releasing hormone, β-endorphin, corticotropin releasing factor and prolactin. Thus, oral hormone contraceptives inhibit the ovulatory process by blocking the activity of the hypothalamus-pituitary-gonadal axis. This inhibitory effect seems to be due to the action of both estrogens and progestins.
1997
2
63
69
Effects of sex steroid hormones on the neuroendocrine system / Genazzani, A. R.; Lucchesi, A.; Stomati, M.; Catarsi, S.; Genazzani, Alessandro; Criscuolo, M.; Petraglia, F.. - In: THE EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE. - ISSN 1362-5187. - STAMPA. - 2:(1997), pp. 63-69.
Genazzani, A. R.; Lucchesi, A.; Stomati, M.; Catarsi, S.; Genazzani, Alessandro; Criscuolo, M.; Petraglia, F.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1108603
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 38
  • ???jsp.display-item.citation.isi??? 0
social impact