An analytical procedure has been developed for the determination of zinc pyrithione in antidandruff formulations. Zinc pyrithione was converted into a stable copper complex and then analysed by reversed-phase HPLC. The proposed method allows the separation of the analyte from related pyrithiones and therefore is able to verify the compliance of cosmetic preparations with current legislation.
ANALYSIS OF PYRITHIONES BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY / Ferioli, Valeria; Rustichelli, Cecilia; Vezzalini, Francesca; Gamberini, G.. - In: CHROMATOGRAPHIA. - ISSN 0009-5893. - ELETTRONICO. - 40:(1995), pp. 669-673.
ANALYSIS OF PYRITHIONES BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
FERIOLI, Valeria;RUSTICHELLI, Cecilia;VEZZALINI, Francesca;
1995
Abstract
An analytical procedure has been developed for the determination of zinc pyrithione in antidandruff formulations. Zinc pyrithione was converted into a stable copper complex and then analysed by reversed-phase HPLC. The proposed method allows the separation of the analyte from related pyrithiones and therefore is able to verify the compliance of cosmetic preparations with current legislation.
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