Sfoglia per Autore  TAGLIAZUCCHI, LORENZO

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Mostrati risultati da 1 a 20 di 31
Titolo Data di pubblicazione Autore(i) File
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes 1-gen-2019 Romito, Filippo; Tagliazucchi, Lorenzo; Pozzi, Cecilia; Mangani, Stefano; Lopresti, Ludovica; Ponterini, Glauco; Costi, Maria Paola
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 1-gen-2021 Tagliazucchi, Lorenzo; Malpezzi, Giulia; Mangani, Stefano; Lopresti, Ludovica; Pozzi, Cecilia; Ponterini, Glauco; Venturelli, Alberto; Costi, Maria Paola
Proteomic contribution to the omic path for the identification of novel drugs overcoming resistance in Leishmaniasis. 1-gen-2021 Tagliazucchi, Lorenzo; Fiorini, Greta; Perea-Martínez, Ana; García- Hernández, Raquel; Ignacio Manzano, José; Costi, Maria Paola; Gamarro, Francisco
Development of guanidino-containing benzimidazoles as novel folate enzymes inhibitors for the treatment of Human African Trypanosomiasis 1-gen-2021 Rizzo, Marco; Francesconi, Valeria; Cichero, Elena; Schenone, Silvia; Tagliazucchi, Lorenzo; Cordeiro da Silva, Anabela; Costi, Maria Paola; Tonelli, Michele
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 1-gen-2021 Tagliazucchi, Lorenzo; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 1-gen-2021 Venturelli, Alberto; Brighenti, Virginia; Tagliazucchi, Lorenzo; Costi, Maria Paola; Pellati, Federica
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 1-gen-2021 Tagliazucchi, Lorenzo; Malpezzi, Giulia; Pozzi, Cecilia; Lopresti, Ludovica; Venturelli, Alberto; D'Arca, Domenico; Marverti, Gaetano; Cecconi, Ciro; Ponterini, Glauco; Costi, Maria Paola
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 1-gen-2021 Lopresti, Ludovica; Pozzi, Cecilia; Tagliazucchi, L; D’Arca, D; Marverti, G; Costi, Mp; Mangani, Stefano
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 1-gen-2021 Tagliazucchi, Lorenzo; Malpezzi, Giulia; Pozzi, Cecilia; Lopresti, Ludovica; Mangani, Stefano; ABDEL LATIF, Andrea; Ponterini, Glauco; Venturelli, Alberto; Costi, Maria Paola
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 1-gen-2021 Marverti, Gaetano; Marraccini, Chiara; Martello, Andrea; D'Arca, Domenico; Pacifico, Salvatore; Guerrini, Remo; Spyrakis, Francesca; Gozzi, Gaia; Lauriola, Angela; Santucci, Matteo; Cannazza, Giuseppe; Tagliazucchi, Lorenzo; Cazzato, Addolorata Stefania; Losi, Lorena; Ferrari, Stefania; Ponterini, Glauco; Costi, Maria P
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 1-gen-2021 Tassone, Giusy; Landi, Giacomo; Linciano, Pasquale; Francesconi, Valeria; Tonelli, Michele; Tagliazucchi, Lorenzo; Costi, Maria Paola; Mangani, Stefano; Pozzi, Cecilia
Structural bases for the synergistic inhibition of human thymidylate synthase and ovarian cancer cell growth by drug combinations 1-gen-2021 Pozzi, C.; Santucci, M.; Marverti, G.; D'arca, D.; Tagliazucchi, L.; Ferrari, S.; Gozzi, G.; Losi, L.; Tassone, G.; Mangani, S.; Ponterini, G.; Costi, M. P.
Repurposing the trypanosomatidic gsk kinetobox for the inhibition of parasitic pteridine and dihydrofolate reductases 1-gen-2021 Santucci, M.; Luciani, R.; Gianquinto, E.; Pozzi, C.; Di Pisa, F.; Dello Iacono, L.; Landi, G.; Tagliazucchi, L.; Mangani, S.; Spyrakis, F.; Costi, M. P.
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 1-gen-2022 Tagliazucchi, Lorenzo; Moschella, MARIA GAETANA; D'Addese, Gianluca; Califano, Daniela; Arenare, Laura; Mezzanzanico, Delia; Chinello, Clizia; Magni, Fulvio; Villani, Marco; Losi, Lorena; Marverti, Gaetano; D'Arca, Domenico; Chiodini, Paolo; Pignata, Sandro; Costi, Maria Paola
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 1-gen-2022 Moschella, Mg; Marverti, G; Cassanelli, Valentina; Venuti, Federica; Tagliazucchi, L; Costi, Mp; D’Arca., D
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 1-gen-2022 Tagliazucchi, L; Rossi, Marianna; Pozzi, Cecilia; Lopresti, Ludovica; Aiello, D; Venturelli, A; Ponterini, G; Costi, Mp
Discovery of guanidino-containing benzimidazoles as novel antifolates for Trypanosomiasis 1-gen-2022 Francesconi, Valeria; Rizzo, Marco; Tagliazucchi, Lorenzo; Pozzi, Cecilia; CORDEIRO DA SILVA, Anabela; Venuti, Federica; Konchie, Claude; Costi, Maria Paola; Michele, Tonelli
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 1-gen-2022 Costi, Maria Paola; Venturelli, A; Ponterini, G; Pozzi, C; Wade, Rebecca; Giovannetti, E; Rimessi, A; Tagliazucchi, L; Moschella, M; Marverti, G; D’Arca, D
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 1-gen-2022 Tagliazucchi, Lorenzo; Venturelli, Alberto; Malpezzi, Giulia; Moschella, MARIA GAETANA; Aiello, Daniele; Lopresti, Ludovica; Pozzi, Cecilia; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
LC-MS/MS Helps Characterizing THP-1 Cells Proteome After Infection with Drug Resistant Leishmania Strains 1-gen-2022 Tagliazucchi, Lorenzo; Perea-Martinez, Ana; Fiorini, Greta; Ignacio Manzano, José; García-Hernández, Raquel; Genovese, Filippo; Pinetti, Diego; Gamarro, Francisco; Costi, Maria Paola
Mostrati risultati da 1 a 20 di 31
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